Hyperthermia Dermal Penetration
Hyperthermia Dermal Penetration Technology uses controlled heat to temporarily increase the permeability of the skin's outer barrier. By raising skin temperature into a mild hyperthermic range, typically around 39°C to 45°C, the stratum corneum becomes more permeable. This can accelerate the transdermal movement of selected drugs, therapeutic agents or cosmetic compounds across the skin barrier.
- Transdermal-delivery protocols using compatible topical compounds
- Cosmetic compound delivery through the skin barrier
- Selected therapeutic-delivery applications
- Protocols where temporary enhancement of skin permeability is desired
- Controlled hyperthermia-assisted topical delivery
- Temporarily increases the permeability of the stratum corneum
- Supports faster transdermal movement of selected compounds
- Uses controlled mild hyperthermia rather than uncontrolled heating
- Can support delivery of selected cosmetic or therapeutic compounds
- Provides a controlled method of temporarily modifying skin-barrier permeability
The stratum corneum normally acts as the skin's primary barrier to substances entering from the surface. Controlled hyperthermia temporarily alters this barrier function. As skin temperature rises within the mild hyperthermic range of approximately 39°C to 45°C, the permeability of the stratum corneum increases, allowing selected compounds to move through the skin more readily. This effect is temporary and is used as part of a controlled transdermal-delivery protocol.
- Cosmetic compound delivery — Uses controlled hyperthermia to temporarily increase skin permeability and support transdermal delivery of selected cosmetic compounds.
- Therapeutic compound delivery — The temporary increase in skin permeability may be used within an appropriate treatment protocol to support delivery of selected therapeutic compounds.
- Drug-delivery application — Hyperthermia-assisted penetration can be used as a transdermal-delivery approach for selected drugs where this forms part of an appropriate clinical protocol.
- Controlled hyperthermic protocol — Skin temperature is raised into a mild hyperthermic range, typically around 39°C to 45°C, to temporarily increase barrier permeability during the delivery phase.
Before treatment, the compound being delivered, treatment area and suitability for a hyperthermia-assisted transdermal protocol are reviewed. Treatment parameters are then selected according to the intended application.
During treatment, controlled heat is applied to the selected skin area. Skin temperature is raised into a mild hyperthermic range, typically around 39°C to 45°C. At this temperature, the stratum corneum becomes temporarily more permeable, supporting transdermal movement of the selected compound.
After the controlled hyperthermic phase ends, the increase in skin-barrier permeability is temporary. Treatment then continues according to the selected transdermal-delivery protocol and any required finishing care.
Hyperthermia Dermal Penetration is used as part of a selected transdermal-delivery protocol rather than as a stand-alone cosmetic treatment. Suitability depends on the compound being delivered, treatment area and intended application.
Hyperthermia Dermal Penetration is a technology applied within a treatment, selected in consultation — it is not booked on its own. See the treatments it may be used within.
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Which technologies are used, and how, is confirmed in consultation and tailored to your goals.